Introduction Facial ageing can involve dermal changes, reduced elasticity and soft-tissue laxity. For some patients, comorbidities may make more invasive medical-aesthetic procedures unsuitable, creating a need to carefully assess alternative approaches. Platelet-rich plasma (PRP) is prepared from a patient’s own blood and contains platelets and associated growth factors; photothermal-bioactivated PRP (PTBA-PRP) or Meta Cell Technology activated PRP adds a light-and-temperatu